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Ask HN: Has anyone here experienced tolerance with Modafinil?

5 points by burnedouthacker 17 years ago · 4 comments · 1 min read


After a day of 200mg(single dose), I cant take it after a week again, because it has no effect. How does it work for you? Any recommendations? Why would you think I am developing this tolerance so fast?

shiny 17 years ago

What I want to know is, how do you guys get this stuff? I wanted to try it awhile back, but couldn't find a legit source on a net that wasn't selling a cheap knockoff from India.

idlewords 17 years ago

I've noticed I can have different physiological responses to the same dose (same batch, same time of day, etc.) I took the stuff regularly for several weeks and mostly stopped because of two side effects - false sense of urgency about everything, and waking up unusually early the day after taking a dose (I was using it for productivity, not sleep avoidance). But I did not notice a drop-off in effectiveness. Still seems to work the same way on the rare occasions I take it now.

replytoburned 17 years ago

6+ years, 200mg daily, no detectable tolerance.

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