Transient improvement in Alzheimer's disease following psilocybin administration

- 10-year history of Alzheimer’s

-monosyllabic speech

- chronic urinary incontinence, executive dysfunction, dysphagia, dependent mobility

- Approximately 19 h post-administration, spontaneous autobiographical speech emerged. Over subsequent days and weeks, functional improvements included restoration of urinary continence, improved ambulation, autonomous dressing, increased emotional responsiveness, sustained social interaction, contextual memory retrieval, preserved working memory for social context, and spontaneous conversational engagement.

Anyone who’s had a loved one with Alzheimer’s would take this in a heartbeat even if the effects are ‘transient’

It’s not clear from the report whether the improvement is described as transient because the patient thereafter quickly reverted to their previous state or whether they simply stopped tracking after a week.