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Show HN: Mycodosing.wtf – Research‑Informed Psychedelic Dosage Calculator

mycodosing.wtf

5 points by ing-norante 5 days ago · 2 comments · 1 min read

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I've been frustrated by existing "magic mushroom dosage calculators": most are either visually rough, only handle cubensis, or hard-code one potency value and ignore species, tolerance, and degradation.

So I built Mycodosing.wtf – a research‑informed calculator that tries to do three things better:

Models species‑level potency using psilocybin/psilocin/baeocystin mg/g with separate profiles for truffles (and syntetics!).

Outputs dose ranges (min/median/max) instead of a single magic number, using per‑species uncertainty factors for real‑world variability.

Includes a tolerance model based on 5‑HT2A receptor downregulation (dose‑dependent exponential decay over ~14 days), plus optional weight adjustment and MAOI flag.

The species potencies are pulled and normalized from LC‑MS/MS and classic chemistry papers (e.g., Garcia‑Romeu 2021, Gotvaldová 2021, Gartz/Stríbrný), then wrapped in a neobrutalist UI built with Vite + React. 100% client-side.

I'd love feedback on:

The dose model itself (any flaws in the math or assumptions?) Species data you'd adjust or supplement What you'd want from a v2

Site: https://mycodosing.wtf/ Code: https://github.com/ing-norante/mycodosing.wtf/

reify 5 days ago

A cool calculator

saved

I spent a good 3 years microdosing.

This seems quite accurate.

The threshold level, recommending a median dose of 0.7g was spot on.

My daily dose was 0.7mg.

I only used my home grown Psilocybe cubensis A+ which is a lot stronger than golden teachers.

  • ing-noranteOP 4 days ago

    Cool! Thanks a lot for testing it and for the comparison with your own regimen, I'm happy that you felt the calculation was accurate.

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