Brain function can start declining 'as early as age 45'

I often wonder about these findings. To what extent are we seeing a neurologically-driven phenomenon vis-a-vis one generated by a host of factors causing relatively common skill atroph? By 45, many people might be working largely on autopilot, causing flexible skills to decline in favor of scripted response.

As someone who just turned 43, this article makes me very sad.

Wait, what was the article about again?