Personalized mRNA vaccine boosts melanoma immunotherapy

3 min read Original article ↗
  • RESEARCH HIGHLIGHT

In patients with resected, high-risk melanoma, the addition of a personalized mRNA-based neoantigen therapy to adjuvant pembrolizumab was more effective than pembrolizumab alone.

By

  1. Karen O’Leary

    1. Karen O’Leary is an Associate Research Analysis Editor with Nature Medicine.

Adjuvant checkpoint inhibitor therapy is the standard of care for resectable melanoma. Although many patients derive lasting benefit from the treatment, a substantial number experience disease recurrence.

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doi: https://doi.org/10.1038/d41591-024-00006-4

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