- RESEARCH HIGHLIGHT
Aged mice engineered to lack granzyme K have improved heart and liver function and less kidney damage.
Age-related stiffening and scarring of liver tissue (pictured) declined in mice that were bioengineered to lack a certain enzyme. Credit: Ziad M. El-Zaatari/Science Photo Library
Researchers have found an enzyme that drives ageing in the body’s tissues1. Drugs that reduce the levels of this protein might one day combat the effects of ageing without impairing the body’s immune defences.
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doi: https://doi.org/10.1038/d41586-026-03638-3
