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Unprecedented results against a stubbornly hard-to-treat cancer are boosting optimism that other challenging tumours will be next.
By
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Heidi Ledford
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Heidi Ledford reports for Nature from Seattle, Washington.
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The landmark success of a drug against an ‘undruggable’ cancer is spurring fresh optimism in the quest to treat seemingly untouchable tumour targets.
doi: https://doi.org/10.1038/d41586-026-01760-w
References
O’Reilly, E. M. et al. N. Engl. J. Med. https://doi.org/10.1056/NEJMoa2605555 (2026).
Pfaff, P. & Shokat, K. M. Biol. Chem. 407, 91–103 (2026).
Garralda, E. et al. Nature Med. 30, 762–771 (2024).
Dumbrava, E. E. et al. New Engl. J. Med. 394, 872–883 (2026).
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