Female mice grow testes after this single DNA tweak

Fieldhouse, Rachel

2 min read Original article ↗
  • NEWS

Small changes in the non-coding part of the genome have a key role in sex determination.

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  1. Rachel Fieldhouse

    1. Rachel Fieldhouse is a reporter for Nature in Sydney, Australia.

Female mouse embryos with a single letter change in a specific region of their DNA develop male reproductive organs, finds a study1 published today in Nature Communications.

Nature 652, 548-549 (2026)

doi: https://doi.org/10.1038/d41586-026-01120-8

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