‘An AlphaFold 4’ — scientists marvel at DeepMind drug spin-off’s exclusive new AI

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Isomorphic Lab’s proprietary drug-discovery model is a major advance, but scientists developing open-source tools are left guessing how to achieve similar results.

Nearly two years after Google DeepMind released AlphaFold 3, an updated version of its system for predicting protein structure that is geared towards drug discovery, its biopharmaceuticals spin-off, Isomorphic Labs, has announced an even more powerful artificial-intelligence model — and the company is keeping the innovation to itself.

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Nature 651, 18 (2026)

doi: https://doi.org/10.1038/d41586-026-00365-7

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