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Analysis of more than one million people shows that mental-health disorders fall into five clusters, each of them linked to a specific set of genetic variants.
Psychiatrists have long relied on diagnostic manuals that regard most mental-health conditions as distinct from one another — depression, for instance, is listed as a separate disorder from anxiety. But a genetic analysis of more than one million people suggests that a host of psychiatric conditions have common biological roots.
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doi: https://doi.org/10.1038/d41586-025-04037-w
References
Grotzinger, A. D. et al. Nature https://doi.org/10.1038/s41586-025-09820-3 (2025).
Zbozinek, T. D. et al. Depress. Anxiety 29, 1065–1071 (2012).
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