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Researchers have identified a neural biomarker of compulsive food cravings, and showed that it is suppressed by the weight-loss drug Mounjaro.
The obesity drug tirzepatide, sold as Mounjaro or Zepbound, can suppress patterns of brain activity associated with food cravings, a study suggests. Researchers measured the changing electrical signals in the brain of a person with severe obesity who had experienced persistent ‘food noise’ — intrusive, compulsive thoughts about eating — shortly after the individual began taking the medication.
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Nature 647, 828-829 (2025)
doi: https://doi.org/10.1038/d41586-025-03766-2
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