Do viruses trigger Alzheimer’s?

1 min read Original article ↗

A growing group of scientists think so, and are asking whether antivirals could treat the disease

In the summer of 2024 several groups of scientists published a curious finding: people vaccinated against shingles were less likely to develop dementia than their unvaccinated peers. Two preprints came from the lab of Pascal Geldsetzer at Stanford University. Analysing medical records from Britain and Australia, the researchers concluded that around a fifth of dementia diagnoses could be averted through the original shingles vaccine, which contains live varicella-zoster virus. Two other studies, one by GSK, a pharmaceutical company, and another by a group of academics in Britain, also reported that a newer “recombinant” vaccine, which is more effective at preventing shingles than the live version, appeared to confer even greater protection against dementia.

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This article appeared in the Science & technology section of the print edition under the headline “A viral hypothesis”

From the March 22nd 2025 edition

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