Elata Biosciences News

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Neuromodulation-inspired gated associative memory networks:extended memory retrieval and emergent multistability

Revolutionary research demonstrates how neuromodulatory agents reshape memory dynamics in neural circuits. If you're keen on deepening your understanding of brain function and potential applications for memory disorders or BCIs, this one definitely merits a gander.

Caudal Granular Insular Cortex to Somatosensory Cortex I: A critical pathway for the transition of acute to chronic pain

The article discusses a critical pathway involving the caudal granular insular cortex and the somatosensory cortex, which plays a significant role in the transition from acute to chronic pain. It provides insights into the neural mechanisms underlying pain and potential targets for treatment.

Recovery of retinal terminal fields after traumatic brain injury: evidence of collateral sprouting and sexual dimorphism

by

Athanasios S. Alexandris

et al.

This research investigates the recovery process of retinal terminal fields following traumatic brain injury, highlighting evidence of collateral sprouting and differing responses based on sexual dimorphism. The findings have implications for understanding recovery mechanisms in neural injury.

Noninvasive MGMT-promotor methylation prediction in high grade gliomas using conventional MRI and deep learning-based segmentations

This research presents a method for predicting MGMT-promotor methylation in high grade gliomas using noninvasive techniques that combine conventional MRI with deep learning-based segmentations.

Individualized Cortico-basal Ganglia Network Effective Connectivity Predicts Outcomes of STN-DBS in Patients with Parkinson's disease

This original research investigates how individualized effective connectivity in the cortico-basal ganglia network can predict outcomes for patients undergoing subthalamic nucleus deep brain stimulation.

NAMI Takes the Lead to Push for Clarity and Safety in AI Mental Health Tools

NAMI collaborates with Harvard-affiliated digital psychiatry researchers led by Dr. John Torous to establish benchmarks for the efficacy of AI tools in mental health support.

Potential beneficial effects of PD-1/PD-L1 blockade in Alzheimer’s disease: a systematic review and meta-analysis of preclinical and clinical studies

This article discusses the potential therapeutic effects of PD-1/PD-L1 blockade in Alzheimer's disease, synthesizing preclinical and clinical studies through a systematic review and meta-analysis.

Associative memory neurons are recruited in PFC-centered circuits to encode schizophrenia-like behavior by dopaminergic receptor-II

The study explores how specific neurons in prefrontal cortex circuits are activated during episodes that mimic schizophrenia behaviors, revealing the role of dopaminergic receptor-II.

Ganglioside sialylation modulates tau internalization and pathology spread

This research investigates how the sialylation of gangliosides affects the internalization of tau proteins and their pathogenic spread in neurodegenerative conditions.

An fMRI-informed EEG model of the amygdala is associated with salience network dynamics during naturalistic emotional stimulation

This study presents a model integrating fMRI and EEG data to understand the role of the amygdala in processing emotional stimuli and its implications for neural salience networks.

Fshr gene depletion prevents recognition memory loss, fat accrual and bone loss in Alzheimer’s mice

by

Uliana Cheliadinova

et al.

This article discusses the consequences of depleting the Fshr gene in models of Alzheimer’s disease, highlighting its protective effects against memory loss and physical degeneration.

IL-27 limits HSPC differentiation during infection and protects from stem cell exhaustion

by

Daniel L Aldridge

et al.

Functional analyses showcase that in the absence of IL-27, hematopoietic stem and progenitor cells are more likely to become monocytes during toxoplasmosis, making them less responsive after infection.

The Impact of Dynamic Reversal Potential on the Evolution of Action Potential Attributes During Spike Trains

by

Ahmed A. Aldohbeyb

et al.

This research investigates how dynamic reversal potentials affect the characteristics of action potentials during spike train activity.

Frontiers in Computational Neuroscience

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Electroacupuncture Exerts Neuroprotective Effects and Alters Gut Microbiota in a MPTP-Induced Mouse Model of Parkinson's Disease

This original research article explores how electroacupuncture not only provides neuroprotective effects in a mouse model of Parkinson's Disease but also significantly alters the gut microbiota composition.

fMRI Signals Often Misread Neural Activity

fMRI signals don’t always match the brain’s true activity levels, overturning a core assumption used in tens of thousands of studies. In about 40% of cases, an increased fMRI signal appeared in regions where neural activity was actually reduced, while decreased signals sometimes showed up in areas with heightened activity.

AI Turns Simple EEG Scans Into Accurate Dementia Detectors

New research shows that deep learning can use EEG signals to distinguish Alzheimer’s disease from frontotemporal dementia with high accuracy.