"I thank God for this blessing and bow to the greatness of the patient nation of Iran" - Iranian President Hassan Rouhani on Twitter, external
"Today, as a result of the actions taken since last July, the United States, our friends and allies in the Middle East, in the entire world are safer because the threat of a nuclear weapon has been reduced" - US Secretary of State John Kerry
"Even after signing the nuclear deal, Iran has not relinquished its ambition to obtain nuclear weapons, and continues to act to destabilise the Middle East and spread terror throughout the world while violating its international commitments" - Israeli Prime Minister Benjamin Netanyahu
"Today, the Obama administration will begin lifting economic sanctions on the world's leading state sponsor of terrorism" - US Republican House Speaker Paul Ryan in a statement, external
"Years of patient and persistent diplomacy, and difficult technical work, have borne fruit as we now implement the deal" - British Foreign Secretary Philip Hammond