John Pelan, Scottish Civic Trust director, said: "Doors Open Days appeals to our natural nosiness to get in and look around all the wonderful buildings that make up our towns and cities.
"We are delighted that Sir Robert and Lady Clerk agreed to the mad idea to Minecraft the amazing Penicuik House and are astonished by the work that ImmersiveMinds have achieved."
Stephen Reid. of ImmersiveMinds, said hours of work went into creating exteriors and interiors of the property.
He said: "The build has taken 86 hours to complete and includes a topographically accurate, 1:1.5 scale landscape and structure comprising over 350,000 blocks, most of which have been retextured to match the look and feel of both incarnations of Penicuik House."
Historic Scotland and Aberdeen Asset Management supported the project.