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mRNA flu vaccine is up to 34.5% more effective than current flu vaccines

scimex.org

32 points by lysp 2 months ago · 21 comments

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fithisux 2 months ago

The current flu vaccines were already effective

  • panja 2 months ago

    Well these are more effective, apparently

    • gitaarik 2 months ago

      According to a Pfizer backed study..

      • signatoremo 2 months ago

        Phase 3 trial, not just any study. The results are required by FDA in order to approve the vaccine.

        • gitaarik 2 months ago

          The point being that it's backed by the company that's producing the product

          • jfengel 2 months ago

            Nobody else is going to back such a study. So that's going to be true for every drug.

            • gitaarik 2 months ago

              Indeed. And pharmaceutical companies will never do studies for medicines they cannot patent. And you can't patent natural medicines, only synthetic. So only the synthetic ones that are created by them are being studied and are the only "proven" medicine.

              Convenient not?

              Maybe we should have an independent institute backed by citizens, that does these studies, for both natural and synthetic medicines.

              But that would destroy the pharmaceutical industry.

              • jfengel 2 months ago

                We do have a small one, The National Center for Complementary and Integrative Health.

                It does a bunch of studies like the ones you suggest, but hasn't yet discovered any blockbuster results.

syntaxing 2 months ago

This is honestly great, I’m especially concerned about my parents as they get older. Though I am curious in the side effects. The flu shot now makes my arm ache. The Covid shot makes me extremely sick for a day though I am willing to pay the price compared to being really sick when I get Covid.

j3th9n 2 months ago

Immune system.

  • wewxjfq 2 months ago

    Is what makes you feel so terrible when you're sick, that's why you don't want to get it involved. Like a car driver would rather not see the seat belt and air bags do their life-saving thing.

    Fun fact: Up to the Civil War or WWI, more soldiers died of illness than of battle wounds. So much for the fabled immune system. And if WWI killed more soldiers in battle, the flu still won that round, because the Spanish Flu killed heaps more later. Now we still remember WWI for its bloodiness, but without Covid-19, who would remember the Spanish Flu?

  • free_bip 2 months ago

    Yeah? What about them?

mikewarot 2 months ago

It's honestly quite frightening the way that mRNA containing compounds can be labeled as a "vaccine", though the mechanism is completely different.

The cells that mRNA reprograms to achieve it's desired result cannot be guaranteed to reside only at the injection site.

  • mikewarot 2 months ago

    Research on the actual distribution of mRNA vacccines through the body is sparse. Here's the relevant quote from something recent[1]

      Lipid nanoparticle mRNA vaccines have revolutionized vaccinology and saved many lives during the COVID-19 pandemic.1 Lipid nanoparticle mRNA vaccines typically contain 5 materials – mRNA, an ionizable lipid, a polyethylene glycol (PEG)–lipid, a helper lipid and cholesterol. Although the vaccines are delivered intramuscularly (IM) and act primarily in the draining lymph node, recent studies have suggested that at least small amounts of the mRNA vaccines may distribute in humans more widely than originally anticipated. A primarily cross-sectional study detected mRNA in blood for up to 15 days after mRNA vaccination.2 Low levels of the vaccine mRNA were detected in breast milk up to 45 hours post-vaccination.3,4 An autopsy study of people dying incidentally after vaccination found mRNA in tissues (axillary lymph nodes and heart) up to 30 days after vaccination.5 Presumably the mRNA reached breast milk and tissues following circulation in blood. Despite evidence in animals and humans that mRNA can be detected in blood after vaccination,2,6 studies of the pharmacokinetics of mRNA lipid nanoparticle components in blood in humans are lacking.
    
    
    
    [1] https://www.medrxiv.org/content/10.1101/2024.07.25.24311039v...

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